SCHEMBL17008148

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4953556	0.87	HSD17B1 (0.38)	HSD17B1HSD17B2SLC6A2SLC6A4SLC6A3
	SCHEMBL21176145	0.86	CYP1A2 (0.40)	HSD17B1HSD17B2SLC6A2SLC6A4SLC6A3
	SCHEMBL20737738	0.85	PDK2 (0.46)	HSD17B1HSD17B2PDK2CYP17A1CYP19A1
	SCHEMBL20737736	0.84	PDK2 (0.39)	HSD17B1HSD17B2ESR1ESR2PDK2
	SCHEMBL20737735	0.84	CYP1A1 (0.41)	PDK2PIM1MAOBCYP1A2
	SCHEMBL20736576	0.84	PDK2 (0.38)	HSD17B1HSD17B2ESR1ESR2PDK2
	SCHEMBL20737731	0.83	PDK2 (0.38)	HSD17B1HSD17B2PDK2
	SCHEMBL20736570	0.83	MEN1 (0.40)	HSD17B1HSD17B2PDK2MAOB
	SCHEMBL20736574	0.83	MEN1 (0.40)	HSD17B1HSD17B2PDK2PIM1MAOB
	SCHEMBL20737692	0.83	PDK2 (0.34)	HSD17B1HSD17B2PDK2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.