Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17009105 | 0.86 | ALOX5 (0.38) | ALOX5PPARAFAAHALDH1A1KMT2A | |
| SCHEMBL17009152 | 0.82 | PPARA (0.46) | ALOX5PPARATHRBPPARG | |
| SCHEMBL17009128 | 0.73 | PPARA (0.47) | PPARAPPARG | |
| SCHEMBL17009120 | 0.69 | PPARA (0.49) | ALOX5PPARAKMT2APPARG | |
| SCHEMBL17009104 | 0.66 | PPARA (0.53) | ALOX5PPARAKMT2APPARG | |
| SCHEMBL17009142 | 0.64 | ALOX5 (0.56) | ALOX5ALDH1A1KMT2AHPGD | |
| SCHEMBL14517130 | 0.62 | PPARA (0.57) | ALOX5PPARAKMT2APPARG | |
| SCHEMBL770755 | 0.60 | CYP2C19 (0.39) | ALDH1A1 | |
| SCHEMBL7625577 | 0.60 | PPARA (0.73) | PPARAALDH1A1PPARGKDM4E | |
| SCHEMBL14526638 | 0.59 | PPARA (0.59) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105205-A1 | PYRAZOLONE COMPOUNDS AND USES THEREOF | Inception 2, Inc. (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2015123133-A1 | PYRAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2, INC. (US) | 2015-08-20 | — | — | WO | disclosed |