Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321991 | 0.88 | MAPT (0.44) | ALDH1A1SMN1; SMN2POLBKMT2AL3MBTL1 | |
| SCHEMBL31561934 | 0.87 | FKBP1A (0.49) | LTA4HALDH1A1MMP2ANPEPFKBP1A | |
| SCHEMBL29273277 | 0.85 | GRM2 (0.50) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL2772367 | 0.83 | LTA4H (0.57) | LTA4HALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL2772130 | 0.83 | LTA4H (0.57) | LTA4HALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL2772128 | 0.83 | LTA4H (0.57) | LTA4HALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL26502806 | 0.81 | FKBP1A (0.43) | ALDH1A1SMN1; SMN2MMP2ANPEPFKBP1A | |
| SCHEMBL2770248 | 0.81 | LTA4H (0.67) | LTA4HALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL2774396 | 0.81 | LTA4H (0.67) | LTA4HALDH1A1SMN1; SMN2FKBP1A | |
| SCHEMBL2770247 | 0.81 | LTA4H (0.67) | LTA4HALDH1A1SMN1; SMN2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123355-A1 | SUBSTITUTED PROLINES / PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS | EOLAS THERAPEUTICS, INC. (US) | 2015-08-20 | — | — | WO | disclosed |