Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17009205 | 0.88 | LTA4H (0.47) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1POLB | |
| SCHEMBL2199015 | 0.88 | MEN1 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3315488 | 0.87 | MEN1 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29273277 | 0.83 | GRM2 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2APKM | |
| SCHEMBL5373647 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5370839 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL11143053 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL27628327 | 0.81 | ALDH1A1 (0.48) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL4663812 | 0.78 | MEN1 (0.49) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8275351 | 0.78 | MEN1 (0.49) | SMN1; SMN2ALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352730-A2 | BIOLOGICALLY ACTIVE AMIDES | H. Lundbeck A/S (DK) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |