Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27908112 | 0.94 | CES2 (0.61) | CES2CES1MAPK1TSHRVCAM1 | |
| Acetonitrile SCHEMBL28068930 | 0.93 | CES2 (0.55) | CES2CES1MAPK1TSHRVCAM1 | |
| SCHEMBL27926228 | 0.89 | ALDH1A1 (0.61) | CES2CES1MAPK1TSHRVCAM1 | |
| SCHEMBL28190153 | 0.88 | VCAM1 (0.58) | CES2CES1MAPK1TSHRVCAM1 | |
| SCHEMBL28081290 | 0.88 | VCAM1 (0.67) | CES2CES1MAPK1TSHRVCAM1 | |
| SCHEMBL28230654 | 0.87 | CES2 (0.54) | CES2CES1MAPK1TSHRVCAM1 | |
| SCHEMBL28230663 | 0.87 | CES2 (0.54) | CES2CES1MAPK1TSHRVCAM1 | |
| Ammonia Solution, Strong SCHEMBL27873079 | 0.87 | VCAM1 (0.65) | CES2CES1MAPK1TSHRVCAM1 | |
| SCHEMBL27747489 | 0.85 | CES2 (0.55) | CES2CES1MAPK1TSHRVCAM1 | |
| SCHEMBL11481380 | 0.84 | VCAM1 (0.57) | CES2CES1MAPK1TSHRVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104277004-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-104326952-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-103180300-B | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-10-07 | — | — | CN | disclosed |
| WO-2015121802-A1 | BENZOYLPHENYL-FORMAMIDINES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE USE | ISAGRO S.P.A. (IT) | 2015-08-20 | — | — | WO | disclosed |
| CN-104326952-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-02-04 | — | — | CN | disclosed |
| CN-104277004-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-01-14 | — | — | CN | disclosed |
| CN-103180300-A | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |
| CN-102203083-A | Pyrimidine derivatives as kinase inhibitors | IRM LLC | 2011-09-28 | — | — | CN | disclosed |