Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18107886 | 0.86 | CA12 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17201292 | 0.83 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25339433 | 0.82 | UCHL1 (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19946099 | 0.82 | GAA (0.38) | LMNATSHRGAAHPGDUCHL1 | |
| SCHEMBL23496925 | 0.82 | KDM4E (0.42) | CYP3A4TSHRGAAHPGDUCHL1 | |
| SCHEMBL18120697 | 0.81 | UCHL1 (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17010234 | 0.80 | TDP1 (0.40) | CA9CYP3A4LMNATSHRGAA | |
| SCHEMBL16005015 | 0.79 | KDM4E (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1918526 | 0.79 | UCHL1 (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20027587 | 0.79 | UCHL1 (0.35) | LMNATSHRGAAHIF1AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190040087-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-07 | — | — | US | disclosed |
| US-20190040087-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-07 | — | — | US | disclosed |
| US-10040806-B2 | Microbiocidally active benzoxaboroles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-07 | — | — | US | disclosed |
| US-10040806-B2 | Microbiocidally active benzoxaboroles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-07 | — | — | US | disclosed |
| US-10040806-B2 | Microbiocidally active benzoxaboroles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-07 | — | — | US | disclosed |
| EP-3107921-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | Syngenta Participations AG (CH) | 2016-12-28 | — | — | EP | disclosed |
| US-20160347773-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-01 | — | — | US | disclosed |
| US-20160347773-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-01 | — | — | US | disclosed |
| US-20160347773-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-01 | — | — | US | disclosed |
| WO-2015121442-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-20 | — | — | WO | disclosed |
| WO-2015121442-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040087-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | MPO, BROX, MANBA | CA12 3032/4885CA1 3955/4885CA2 2692/4885 |
| US-20160347773-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | MPO, BROX, MANBA | CA12 3032/4885CA1 3955/4885CA2 2692/4885 |
| US-10040806-B2 | Microbiocidally active benzoxaboroles | MPO, BROX, MANBA | CA12 3032/4885CA1 3955/4885CA2 2692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.