SCHEMBL1701034

SCHEMBL1701034

O=c1ccoc(C(F)(F)C(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700927 0.87 MAPT (0.36) ALDH1A1HPGD
SCHEMBL571449 0.74 NPC1 (0.34)
SCHEMBL2116183 0.61
SCHEMBL21038125 0.61 ALDH1A1 (0.33) ALDH1A1HPGD
SCHEMBL1187892 0.61
SCHEMBL3605686 0.61
SCHEMBL31604210 0.61
SCHEMBL7532803 0.61
SCHEMBL2405291 0.61
SCHEMBL9812785 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116925023-A Improved synthesis of 2-perfluoroalkyl-4H-pyran-4-one derivatives 江苏桐孚高新材料有限公司 2023-10-24 CN disclosed
EP-2585436-B1 PROCESS FOR PREPARING 4-HYDROXYPYRIDINES BASF SE (DE) 2015-03-18 EP disclosed
US-8716487-B2 Process for preparing 4-hydroxypyridines BASF SE (DE) 2014-05-06 US disclosed
EP-2585436-A1 PROCESS FOR PREPARING 4-HYDROXYPYRIDINES BASF SE (DE) 2013-05-01 EP disclosed
US-20130096312-A1 Process for Preparing 4-hydroxypyridines BASF SE (DE) 2013-04-18 US disclosed
WO-2011161612-A1 PROCESS FOR PREPARING 4-HYDROXYPYRIDINES BASF SE (DE) 2011-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096312-A1 Process for Preparing 4-hydroxypyridines QDPR, HRH4, CYP4B1 ALDH1A1 337/4885HPGD 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.