Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 10/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15274946 | 0.84 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12184971 | 0.84 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15274951 | 0.84 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4584716 | 0.84 | PSEN1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3823482 | 0.84 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL751367 | 0.84 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3339737 | 0.84 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29779351 | 0.84 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11127173 | 0.84 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29393803 | 0.84 | SIGMAR1 (0.54) | SIGMAR1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9112157-B2 | Hole transport materials including OLED applications | SOLVAY USA, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-9112157-B2 | Hole transport materials including OLED applications | SOLVAY USA, INC. (US) | 2015-08-18 | — | — | US | disclosed |