SCHEMBL17010989

SCHEMBL17010989

c1ccc(-c2ccc(N(c3ccc4sccc4c3)c3ccc4sccc4c3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.46
CA12 O43570 8/20 0.46
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
DYRK1A Q13627 1/20 0.42
CTNNB1 P35222 1/20 0.41
WNT3A P56704 1/20 0.41
CYP2A6 P11509 2/20 0.39
PER2 O15055 1/20 0.36
CRY1 Q16526 1/20 0.36
CRY2 Q49AN0 1/20 0.36
PIK3CD O00329 1/20 0.36
PTPRC P08575 1/20 0.36
PTPN6 P29350 1/20 0.36
PTPN11 Q06124 1/20 0.36
PTPN22 Q9Y2R2 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17740653 0.98 CA2 (0.45) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL10051791 0.97 CA2 (0.46) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL20386530 0.91 SLC6A2 (0.47) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL24368651 0.88 CA2 (0.48) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL17011002 0.87 CA12 (0.37) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL929430 0.86 CYP2A6 (0.48) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL26546158 0.85 ALDH1A1 (0.36) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL26542795 0.85 ALDH1A1 (0.36) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL24368899 0.84 CA2 (0.50) CA2CA12SLC6A2SLC6A4SLC6A3
SCHEMBL24368898 0.84 CA2 (0.50) CA2CA12SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9112157-B2 Hole transport materials including OLED applications SOLVAY USA, INC. (US) 2015-08-18 US disclosed
US-9112157-B2 Hole transport materials including OLED applications SOLVAY USA, INC. (US) 2015-08-18 US disclosed