SCHEMBL17011002

SCHEMBL17011002

c1ccc(-c2ccc(N(c3ccc4ccsc4c3)c3ccc4ccsc4c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.37
CA2 P00918 3/20 0.37
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
BACE1 P56817 1/20 0.33
DHODH Q02127 1/20 0.33
PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26546158 0.98 ALDH1A1 (0.36) CA12CA2ESR1ESR2SLC6A2
SCHEMBL26542795 0.98 ALDH1A1 (0.36) CA12CA2ESR1ESR2SLC6A2
SCHEMBL10051792 0.97 ALDH1A1 (0.37) CA12CA2SLC6A2SLC6A4SLC6A3
SCHEMBL21872956 0.91 ALDH1A1 (0.41) CA12CA2SLC6A2SLC6A4SLC6A3
SCHEMBL31314474 0.91 ALDH1A1 (0.41) CA12CA2SLC6A2SLC6A4SLC6A3
SCHEMBL24368904 0.89 ESR1 (0.42) CA12CA2ESR1ESR2KDM4E
SCHEMBL17010989 0.87 CA2 (0.46) CA12CA2SLC6A2SLC6A4SLC6A3
SCHEMBL26542802 0.87 KDM4E (0.32) CA12CA2SLC6A2SLC6A4SLC6A3
SCHEMBL26546046 0.87 GPR3 (0.35) CA12CA2SLC6A2SLC6A4SLC6A3
SCHEMBL17740653 0.85 CA2 (0.45) CA12CA2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9112157-B2 Hole transport materials including OLED applications SOLVAY USA, INC. (US) 2015-08-18 US disclosed
US-9112157-B2 Hole transport materials including OLED applications SOLVAY USA, INC. (US) 2015-08-18 US disclosed