Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370725 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12370702 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12370726 | 0.75 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14080663 | 0.75 | ADRA2A (0.31) | MEN1KMT2AHTT | |
| SCHEMBL827011 | 0.74 | CA12 (0.49) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12370736 | 0.74 | ALDH1A1 (0.50) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12370714 | 0.74 | ALDH1A1 (0.53) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14080729 | 0.73 | ADRA2A (0.34) | MEN1KMT2AHTT | |
| SCHEMBL12370708 | 0.72 | KDM4E (0.50) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12370719 | 0.72 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765264-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |