Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370726 | 0.97 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL12370714 | 0.92 | ALDH1A1 (0.53) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL12370736 | 0.89 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL19912060 | 0.85 | ALDH1A1 (0.54) | KDM4EALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL12370725 | 0.84 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL12370702 | 0.83 | SMN1; SMN2 (0.46) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL28779833 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL12370704 | 0.83 | SMN1; SMN2 (0.51) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 | |
| Allylanisole SCHEMBL4737421 | 0.80 | KCNA3 (0.58) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12370724 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765264-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765263-B1 | DENTAL COMPOSITION CONTAINING SI-H FUNCTIONAL CARBOSILANE COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-1765261-B1 | DENTAL COMPOSITION CONTAINING UNSATURATED CARBOSILANE CONTAINING COMPONENTS | MINNESOTA MINING MFG GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003711-B2 | Dental composition containing Si-H functional carbosilane components | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-08-23 | — | — | US | disclosed |
| US-7915324-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7915324-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-03-29 | — | — | US | disclosed |
| EP-1765265-B1 | DENTAL COMPOSITION CONTAINING AN EPOXY FUNCTIONAL CARBOSILANE COMPOUND | 3M ESPE AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-7799846-B2 | Dental composition containing an epoxy functional carbosilane compound | 3M ESPE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799846-B2 | Dental composition containing an epoxy functional carbosilane compound | 3M ESPE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7662869-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| US-7662869-B2 | Curable di- or polyunsaturated carbosilane containing silicon-aryl bondand no silicon-oxygen bonds; initiator, filler, dyes, pigments, thixotropic agents, flow control agents, polymeric thickeners, surfactants, odorous substances, diluting agent(s) and flavors; crowns, bridges | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-02-16 | — | — | US | disclosed |
| US-20080070193-A1 | Dental Composition Containing Unsaturated Carbosilane Containing Components | 3M DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080070193-A1 | Dental Composition Containing Unsaturated Carbosilane Containing Components | 3M DEUTSCHLAND GMBH (DE) | 2008-03-20 | — | — | US | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | 3M DEUTSCHLAND GMBH (DE) | 2007-10-11 | — | — | US | disclosed |
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-06 | — | — | US | disclosed |
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | 3M INNOVATIVE PROPERTIES COMPANY | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238803-A1 | Dental Composition Containing Si-H Functional Carbosilane Components | TAS2R41, TAS2R42, TAS1R1 | KDM4E 2817/4885ALDH1A1 1450/4885SMN1; SMN2 3074/4885 |
| US-20070207443-A1 | Dental composition containing unsaturated carbosilane containing components | TAS1R1, TAS2R41, TAS2R39 | KDM4E 3707/4885ALDH1A1 1136/4885SMN1; SMN2 2829/4885 |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | EPX, TAS2R41, TAS1R1 | KDM4E 2022/4885ALDH1A1 1405/4885SMN1; SMN2 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.