Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014290 | 0.91 | HTR2A (0.37) | HTR2AHTR2CHTR2BSIGMAR1DRD4 | |
| SCHEMBL17014283 | 0.82 | SIGMAR1 (0.42) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL17019568 | 0.76 | DRD4 (0.34) | HTR2AHTR2CHTR2BSIGMAR1DRD4 | |
| SCHEMBL18870922 | 0.75 | DRD4 (0.33) | HTR2AHTR2CHTR2BSIGMAR1DRD4 | |
| SCHEMBL17019722 | 0.69 | SIGMAR1 (0.33) | HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL17014289 | 0.69 | HTT (0.30) | — | |
| SCHEMBL18870237 | 0.68 | HTR2A (0.36) | HTR2AHTR2CHTR2BSIGMAR1DRD4 | |
| SCHEMBL17014520 | 0.68 | P2RX7 (0.31) | — | |
| SCHEMBL17014270 | 0.66 | — | — | |
| SCHEMBL17014510 | 0.65 | HTR2A (0.36) | HTR2AHTR2CHTR2BSIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | HAVCR2, SLC10A1, SORD | HTR2A 4319/4885HTR2C 2628/4885HTR2B 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.