Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014309 | 0.78 | NOTUM (0.39) | NOTUMDRD2 | |
| SCHEMBL15585945 | 0.77 | NOTUM (0.35) | NOTUMKDM4EALDH1A1HPGDDRD2 | |
| SCHEMBL17014307 | 0.76 | NOTUM (0.32) | NOTUM | |
| SCHEMBL16577454 | 0.73 | NOTUM (0.35) | NOTUMDRD2 | |
| SCHEMBL17014362 | 0.73 | NOTUM (0.33) | NOTUM | |
| SCHEMBL17014323 | 0.72 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDDRD2 | |
| SCHEMBL15692841 | 0.71 | NOTUM (0.33) | NOTUM | |
| SCHEMBL23849740 | 0.70 | DRD2 (0.42) | NOTUMKDM4EALDH1A1HPGDDRD2 | |
| SCHEMBL17014336 | 0.69 | DRD2 (0.37) | NOTUMKDM4EALDH1A1HPGDDRD2 | |
| SCHEMBL16577360 | 0.69 | NOTUM (0.40) | NOTUMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232509-A1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | HAVCR2, SLC10A1, SORD | NOTUM 2968/4885KDM4E 4762/4885ALDH1A1 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.