Phenylalanine

Phenylalanine

SCHEMBL1701460

C[C@@H](N)Cc1c[nH]c(C(=O)O)n1.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 5/20 0.54
ALPI P09923 1/20 0.54
PKM P14618 1/20 0.54
PTGS1 P23219 1/20 0.54
XIAP P98170 1/20 0.54
SLC6A2 P23975 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
MAOA P21397 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
CYP2A6 P11509 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7866907 0.85 HRH4 (0.35) SLC7A5SLC6A2TAAR1MAOASLC6A4
Cysteine SCHEMBL2769343 0.84 PTGS1 (0.42) SLC7A5ALPIPKMPTGS1XIAP
Aspartic Acid SCHEMBL5885290 0.84 SLC7A5 (0.35) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL9171481 0.81 HTR2A (0.38) SLC6A2SLC6A4SLC6A3LMNABLM
Phenylalanine SCHEMBL579042 0.78 SLC7A5 (0.81) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL579040 0.78 SLC7A5 (0.81) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL949037 0.75 BRD4 (0.43) LMNATSHRHIF1A
SCHEMBL9717841 0.75 CYP1A2 (0.43) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL9717852 0.75 CYP1A2 (0.43) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28995223 0.75 SLC7A5 (0.96) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3951939-A ISOLATION FROM SEA-ANEMONES BEHRINGWERKE AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed
WO-2011127418-A1 BTNL9 PROTEINS, NUCLEIC ACIDS, AND ANTIBODIES AND USES THEREOF AMGEN INC. (US) 2011-10-13 WO disclosed