Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL2769343 | 0.89 | PTGS1 (0.42) | ALDH1A1CYP1A2NFKB1MEN1KMT2A | |
| Aspartic Acid SCHEMBL5885290 | 0.89 | SLC7A5 (0.35) | ALDH1A1CYP1A2NFKB1MEN1KMT2A | |
| SCHEMBL9171481 | 0.85 | HTR2A (0.38) | ALDH1A1BLMNPSR1LMNASLC6A2 | |
| SCHEMBL11039378 | 0.80 | CASR (0.32) | BLMNPSR1 | |
| SCHEMBL15951853 | 0.78 | ALOX5 (0.30) | — | |
| SCHEMBL5989125 | 0.77 | MAOA (0.33) | LMNAMAOA | |
| SCHEMBL9717841 | 0.75 | CYP1A2 (0.43) | ALDH1A1CYP1A2NFKB1MEN1KMT2A | |
| SCHEMBL9717852 | 0.75 | CYP1A2 (0.43) | ALDH1A1CYP1A2NFKB1MEN1KMT2A | |
| SCHEMBL29956837 | 0.74 | HCAR2 (0.33) | NPSR1LMNA | |
| SCHEMBL26288426 | 0.73 | HRH4 (0.40) | HRH4HRH3ALDH1A1CYP1A2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689590-A4 | TOTALLY SYNTHETIC AFFINITY REAGENTS | UNIV NORTH CAROLINA (US) | 2001-05-23 | — | — | EP | claimed |
| EP-0689590-A1 | TOTALLY SYNTHETIC AFFINITY REAGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-01-03 | — | — | EP | claimed |
| WO-1994018318-A1 | TOTALLY SYNTHETIC AFFINITY REAGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-08-18 | — | — | WO | claimed |
| CN-112608282-B | Compound containing quinazolinedione and N-O structure and preparation method and application thereof | 山东先达农化股份有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114760988-A | Bicyclic peptide ligands specific for EphA2 and uses thereof | 拜斯科技术开发有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-113999290-B | Stable leuprorelin acetate and application thereof | 浙江湃肽生物有限公司南京分公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-113999290-A | High-stability leuprorelin acetate and application thereof | 浙江湃肽生物有限公司南京分公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-111484963-A | Process for producing L-amino acid | 味之素株式会社 | 2020-08-04 | — | — | CN | disclosed |
| CN-110741015-A | Compositions and methods for treating and/or preventing pathogenic fungal infections and maintaining microbiome symbiosis | 芝加哥大学 | 2020-01-31 | — | — | CN | disclosed |
| CN-108676024-B | The near-infrared squaraine dye and its preparation method and application of phenyl boric acid modification | 福州大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-1236760-C | Liposomes containing entrapped compound in supersaturated solution | ALZA CORP (US) | 2006-01-18 | — | — | CN | disclosed |
| CN-1617716-A | Heterocycle derivatives and methods of use | UNIV TEXAS (US) | 2005-05-18 | — | — | CN | disclosed |
| CN-1418112-A | Peptidase cleavable, targeted antineoplastic agents and therapeutic uses thereof | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2003-05-14 | — | — | CN | disclosed |
| CN-1396822-A | Liposomes containing entrapped compound in supersaturated solution | ALZA CORP (US) | 2003-02-12 | — | — | CN | disclosed |