SCHEMBL17014609

SCHEMBL17014609

Brc1cccc(-c2cc(-c3ccccc3)c3c(c2-c2ccccc2)-c2cccc4cccc-3c24)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.39
MAOA P21397 1/20 0.39
ALDH1A1 P00352 6/20 0.38
TSHR P16473 5/20 0.38
HPGD P15428 3/20 0.38
MAPK1 P28482 3/20 0.38
HSD17B10 Q99714 3/20 0.38
TP53 P04637 2/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HIF1A Q16665 1/20 0.38
BIRC5 O15392 1/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
RAB9A P51151 4/20 0.37
NPC1 O15118 3/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 4/20 0.37
HTT P42858 2/20 0.37
IDO1 P14902 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16670590 0.97 MAOB (0.39) MAOBMAOAALDH1A1TSHRHPGD
SCHEMBL24067765 0.91 BIRC5 (0.39) MAOBMAOAALDH1A1TSHRHPGD
SCHEMBL30040403 0.91 BIRC5 (0.39) MAOBMAOAALDH1A1TSHRHPGD
SCHEMBL30041352 0.91 ALDH1A1 (0.38) MAOBMAOAALDH1A1TSHRHPGD
SCHEMBL24067815 0.91 ALDH1A1 (0.38) MAOBMAOAALDH1A1TSHRHPGD
SCHEMBL30040588 0.89 ALDH1A1 (0.42) MAOBALDH1A1TSHRHPGDMAPK1
SCHEMBL13002341 0.89 ALDH1A1 (0.42) MAOBALDH1A1TSHRHPGDMAPK1
SCHEMBL17014606 0.89 ALDH1A1 (0.42) MAOBALDH1A1TSHRHPGDMAPK1
SCHEMBL16859291 0.89 ALDH1A1 (0.44) ALDH1A1TSHRHPGDMAPK1HSD17B10
SCHEMBL2158220 0.89 ALDH1A1 (0.47) ALDH1A1TSHRHPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128259-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-04-27 US disclosed
US-20230128259-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-04-27 US disclosed
US-20230128259-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2023-04-27 US disclosed
CN-115279732-A Compound and organic light emitting device including the same 株式会社LG化学 2022-11-01 CN disclosed
WO-2021241900-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-12-02 WO disclosed
WO-2021241900-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-12-02 WO disclosed
EP-2924020-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2015-09-30 EP disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128259-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME L1CAM, CRY1, CRY2 MAOB 1715/4885MAOA 1807/4885ALDH1A1 22/4885
US-20150236273-A1 FLUORANTHENE COMPOUND, AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME AFF2, ESR1, AFF4 MAOB 517/4885MAOA 237/4885ALDH1A1 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.