Sugi Predict

Sugi Predict / Compounds / SCHEMBL170150

SCHEMBL170150

SCHEMBL170150

C=CCOP(=O)(O)OCC(O)CO

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ SELP P16109 1/20 0.36
▸ CA1 P00915 1/20 0.35
▸ CA2 P00918 1/20 0.35
▸ CA7 P43166 1/20 0.35
▸ BTN3A1 O00481 2/20 0.31
▸ MPI P34949 1/20 0.31
▸ P2RY10 O00398 4/20 0.30
▸ GPR174 Q9BXC1 3/20 0.30
▸ GPR34 Q9UPC5 2/20 0.30
▸ LPAR2 Q9HBW0 1/20 0.30
▸ LPAR3 Q9UBY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9279694 1.00 SMN1; SMN2 (0.37) SMN1; SMN2SELPCA1CA2CA7
Glycerin SCHEMBL28926734 0.91 LMNA (0.36) SMN1; SMN2CA1CA2CA7BTN3A1
SCHEMBL12284729 0.84 SMN1; SMN2 (0.46) SMN1; SMN2SELPMPIP2RY10GPR174
SCHEMBL30148756 0.84 SMN1; SMN2 (0.46) SMN1; SMN2SELPMPIP2RY10GPR174
SCHEMBL29708086 0.84 SMN1; SMN2 (0.46) SMN1; SMN2SELPMPIP2RY10GPR174
SCHEMBL579431 0.84 SMN1; SMN2 (0.46) SMN1; SMN2SELPMPIP2RY10GPR174
SCHEMBL24111174 0.82 SMN1; SMN2 (0.44) SMN1; SMN2SELPMPIP2RY10GPR174
SCHEMBL12281973 0.82 SMN1; SMN2 (0.44) SMN1; SMN2SELPMPIP2RY10GPR174
SCHEMBL17513028 0.82 SMN1; SMN2 (0.44) SMN1; SMN2SELPMPIP2RY10GPR174
SCHEMBL12282496 0.82 SMN1; SMN2 (0.44) SMN1; SMN2SELPMPIP2RY10GPR174

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130197038-A1 Compositions And Methods For Neovascularization MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-08-01 — — US claimed
EP-2313455-A1 PEG-FREE EMULSIFIERS Dr. W. Kolb AG (CH) 2011-04-27 — — EP claimed
WO-2010017651-A1 PEG-FREE EMULSIFIERS DR. W. KOLB AG (CH) 2010-02-18 — — WO claimed
JP-60061030-A — — None — — JP disclosed
US-10071110-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-09-11 — — US disclosed
US-20170239279-A1 PHOSPHONATE COMPOUNDS UNIV CALIFORNIA (US) 2017-08-24 — — US disclosed
US-9649321-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-05-16 — — US disclosed
US-9446031-B2 Compositions and methods for neovascularization NATIONAL UNIVERSITY OF SINGAPORE (SG) 2016-09-20 — — US disclosed
US-20160067268-A1 PHOSPHONATE COMPOUNDS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-10 — — US disclosed
US-9206208-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-12-08 — — US disclosed
US-20150051174-A1 Phosphonate Compounds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-02-19 — — US disclosed
US-6716825-B2 OSTEOPOROSIS AND OTHER DISORDERS OF BONE METABOLISUM, CANCER, VIRAL INFECTIONS, AND THE LIKE. THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-06 — — US disclosed
CN-1477147-A Synthesis of oily chemical product with multifunctional group, its product and its application ���Ⱥ;� 2004-02-25 — — CN disclosed
US-20040019232-A1 Analogs of phosphonate and bisphosphonate compounds based on bone resorption suppressors (alendronic acid), viricides (cidofovir) and antineoplastic agents (bemcitabine); nontoxic; bioavailability; side effects reduction NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-01-29 — — US disclosed
EP-1233770-A4 PHOSPHONATE COMPOUNDS UNIV CALIFORNIA AT SAN DIEGO (US) 2003-04-16 — — EP disclosed
EP-1233770-A2 PHOSPHONATE COMPOUNDS The Regents of The University of California at San Diego (US) 2002-08-28 — — EP disclosed
WO-2001039724-A2 PHOSPHONATE COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) 2001-06-07 — — WO disclosed
WO-2000035327-A1 WET OR DRY WEB DISPENSER KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-06-22 — — WO disclosed
US-4916249-A ANTITUMOR AGENTS CLARION FUND, INC. 1990-04-10 — — US disclosed
JP-S6061030-A EMULSIFYING SOLUBILIZER NIPPON SAAFUAKUTANTO KOGYO KK 1985-04-08 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051174-A1 Phosphonate Compounds PHPT1, PHOSPHO1, PIK3CA SMN1; SMN2 2978/4885SELP 1788/4885CA1 4092/4885
US-10071110-B2 Phosphonate compounds PHPT1, PHOSPHO1, PIK3CA SMN1; SMN2 2978/4885SELP 1788/4885CA1 4092/4885
US-20040019232-A1 Analogs of phosphonate and bisphosphonate compounds based on bone resorption suppressors (alendronic acid), viricides (cidofovir) and antineoplastic agents (bemcitabine); nontoxic; bioavailability; side effects reduction BPGM, PPA1, INPP5D SMN1; SMN2 3446/4885SELP 3788/4885CA1 3775/4885
US-20170239279-A1 PHOSPHONATE COMPOUNDS PHPT1, PHOSPHO1, PIK3CA SMN1; SMN2 2978/4885SELP 1788/4885CA1 4092/4885
US-20160067268-A1 PHOSPHONATE COMPOUNDS PHPT1, PHOSPHO1, PIK3CA SMN1; SMN2 2978/4885SELP 1788/4885CA1 4092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.