Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792345 | 0.84 | CA12 (0.52) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL10792348 | 0.84 | CA12 (0.52) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL23384507 | 0.83 | CA12 (0.50) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL27909731 | 0.83 | CA12 (0.50) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL27927456 | 0.83 | CA12 (0.50) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL13086357 | 0.81 | CA12 (0.48) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL13645688 | 0.80 | CA14 (0.45) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL2491150 | 0.79 | DPP4 (0.50) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30698081 | 0.79 | CA12 (0.47) | CA12CA14BIRC2TSHRSMN1; SMN2 | |
| SCHEMBL6467689 | 0.79 | CA12 (0.47) | CA12CA14BIRC2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | UNIV NEW YORK (US) | 2017-08-31 | — | — | US | disclosed |
| US-9593142-B2 | Aldehyde capture ligation technology for synthesis of amide bonds | NEW YORK UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | NEW YORK UNIVERSITY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | CA12 673/4885CA14 708/4885BIRC2 902/4885 |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | CA12 673/4885CA14 708/4885BIRC2 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.