Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15242984 | 0.89 | RAB9A (0.44) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL16856726 | 0.85 | LMNA (0.41) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL16856698 | 0.81 | CYP19A1 (0.48) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL16856766 | 0.75 | SIGMAR1 (0.46) | SMN1; SMN2ALDH1A1HTTNPC1MAPT | |
| SCHEMBL15243035 | 0.72 | CYP11B1 (0.46) | ALDH1A1HTTKMT2AMEN1MAPT | |
| SCHEMBL16856696 | 0.72 | GRM2 (0.47) | SMN1; SMN2ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL22001014 | 0.72 | TP53 (0.57) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL15242943 | 0.69 | KMT2A (0.47) | ALDH1A1HTTRAB9ANPC1KMT2A | |
| SCHEMBL10194247 | 0.69 | CYP19A1 (0.61) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL15243034 | 0.69 | CYP19A1 (0.56) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586912-B2 | 2-substituted-2H-1, 2, 3-triazole derivative and its preparation method | ABA CHEMICALS CORPORATION (CN) | 2017-03-07 | — | — | US | disclosed |
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | ABA CHEMICALS CORPORATION (CN) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232431-A1 | 2-SUBSTITUTED-2H-1, 2, 3-TRIAZOLE DERIVATIVE AND ITS PREPARATION METHOD | CYP1A2, CYP1B1, CYP3A5 | SMN1; SMN2 4317/4885ALDH1A1 104/4885HTT 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.