SCHEMBL17015201

SCHEMBL17015201

c1ccc(-n2ccc3c2ccc2c4ccccc4n(-c4cccc(-c5c6ccccc6cc6ccccc56)c4)c23)cc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALOX5 P09917 2/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
WNK1 Q9H4A3 1/20 0.31
BIRC5 O15392 1/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17015660 0.97 ALOX5 (0.34) KDM4EATML3MBTL1ALOX5KMT2A
SCHEMBL17016145 0.95 L3MBTL1 (0.39) KDM4EATML3MBTL1ALOX5KMT2A
SCHEMBL17015742 0.94 KDM4E (0.33) KDM4EATML3MBTL1ALOX5KMT2A
SCHEMBL17015196 0.92 L3MBTL1 (0.38) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17016148 0.91 KDM4E (0.39) KDM4EATML3MBTL1ALOX5KMT2A
SCHEMBL17015197 0.91 KDM4E (0.39) KDM4EATML3MBTL1ALOX5KMT2A
SCHEMBL15632449 0.90 L3MBTL1 (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17015664 0.90 ALOX5 (0.35) KDM4EATML3MBTL1ALOX5KMT2A
SCHEMBL15684055 0.89 ATM (0.40) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17015194 0.89 KDM4E (0.34) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME INMT, IDO1, IDO2 KDM4E 1286/4885ATM 3623/4885L3MBTL1 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.