SCHEMBL17015378

SCHEMBL17015378

O=C(c1ccc(-n2c3ccccc3c3ccc4ccn(-c5ccccc5)c4c32)cc1)c1ccc2ccccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.40
TSHR P16473 3/20 0.39
LMNA P02545 2/20 0.39
CNR2 P34972 2/20 0.39
GMNN O75496 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
CNR1 P21554 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
THPO P40225 1/20 0.39
MTOR P42345 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
HIF1A Q16665 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17016253 1.00 ACHE (0.40) ACHETSHRLMNACNR2GMNN
SCHEMBL17015379 0.94 CLK1 (0.40) ACHETSHRLMNACNR2GMNN
SCHEMBL17016254 0.94 CLK1 (0.40) ACHETSHRLMNACNR2GMNN
SCHEMBL17016249 0.92 L3MBTL1 (0.40) TSHRLMNACNR2CYP1A2CYP3A4
SCHEMBL17015374 0.92 L3MBTL1 (0.40) TSHRLMNACNR2CYP1A2CYP3A4
SCHEMBL17016323 0.91 SRC (0.39) ACHETSHRLMNACNR2GMNN
SCHEMBL17016250 0.89 ATM (0.39) TSHRCNR2HPGDMEN1NPC1
SCHEMBL17015376 0.89 L3MBTL1 (0.39) CNR2HPGDALOX15BLMMEN1
SCHEMBL17016183 0.88 CNR2 (0.38) ACHETSHRLMNACNR2GMNN
SCHEMBL17015226 0.88 CNR2 (0.38) ACHETSHRLMNACNR2GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME INMT, IDO1, IDO2 ACHE 214/4885TSHR 4076/4885LMNA 2754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.