Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 4/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 5/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008501 | 0.86 | LRRK2 (0.41) | LRRK2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL18567054 | 0.86 | LRRK2 (0.41) | LRRK2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL31086658 | 0.86 | LRRK2 (0.41) | LRRK2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL17017528 | 0.85 | HCK (0.35) | LRRK2MEN1KMT2ASRCHCK | |
| SCHEMBL28588449 | 0.83 | LRRK2 (0.45) | LRRK2MEN1KMT2AJAK2JAK1 | |
| SCHEMBL17017125 | 0.83 | PIK3C3 (0.37) | MEN1KMT2ASRCHCKMAPK12 | |
| SCHEMBL17017907 | 0.82 | MRGPRX4 (0.40) | LRRK2MEN1KMT2ASRCHCK | |
| SCHEMBL17008491 | 0.82 | LMNA (0.40) | LRRK2MEN1ALDH1A1KMT2ASRC | |
| SCHEMBL31086600 | 0.82 | LMNA (0.40) | LRRK2MEN1ALDH1A1KMT2ASRC | |
| SCHEMBL17008500 | 0.81 | LRRK2 (0.46) | LRRK2JAK2JAK1TYK2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015121660-A1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2015-08-20 | — | — | WO | disclosed |