Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | HCK | P08631 | 8/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17017129 | 0.89 | MRGPRX4 (0.40) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL18567060 | 0.88 | MRGPRX4 (0.42) | MRGPRX4HCKMAPK12MAPK14SRC | |
| Hydrochloric Acid SCHEMBL17008549 | 0.88 | MRGPRX4 (0.40) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL31086848 | 0.85 | CTSV (0.43) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL17008498 | 0.85 | CTSV (0.43) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL17017643 | 0.82 | LRRK2 (0.41) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL17008543 | 0.81 | MAPK14 (0.45) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL17008477 | 0.80 | MRGPRX4 (0.39) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL17017125 | 0.79 | PIK3C3 (0.37) | MRGPRX4HCKMAPK12MAPK14SRC | |
| SCHEMBL17017799 | 0.78 | GABRA1 (0.41) | HCKMAPK12MAPK14SRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015121660-A1 | PYRAZOLYL-UREAS AS KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2015-08-20 | — | — | WO | disclosed |