Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP8 | P22894 | 4/20 | 0.42 |
| ▸ | MMP12 | P39900 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 4/20 | 0.42 |
| ▸ | MMP14 | P50281 | 4/20 | 0.42 |
| ▸ | MMP16 | P51512 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17022164 | 0.82 | BCL9 (0.49) | KMT2AGAACA2CA9ALDH1A1 | |
| SCHEMBL11042825 | 0.80 | PKM (0.51) | L3MBTL1GAACA2CA9CA12 | |
| SCHEMBL10364238 | 0.79 | CA1 (0.54) | TDP1MMP2MMP8MMP12MMP13 | |
| SCHEMBL17019166 | 0.78 | CA2 (0.52) | CA2CA9CA12CA1CA5A | |
| SCHEMBL22531363 | 0.77 | MTNR1A (0.47) | L3MBTL1MMP2MMP8MMP12MMP13 | |
| SCHEMBL29549289 | 0.77 | MTNR1A (0.47) | L3MBTL1MMP2MMP8MMP12MMP13 | |
| SCHEMBL4662818 | 0.74 | CA2 (0.47) | KMT2ACA2CA9CA12CA1 | |
| SCHEMBL789755 | 0.72 | SMN1; SMN2 (0.60) | TDP1L3MBTL1KMT2ALMNAALDH1A1 | |
| SCHEMBL4749786 | 0.72 | CA1 (0.49) | MMP2MMP8MMP12MMP13MMP14 | |
| SCHEMBL10362231 | 0.72 | AKR1B1 (0.59) | TDP1MMP2MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232434-A1 | STAT3 INHIBITORS AND THEIR ANTICANCER USE | OHIO STATE INNOVATION FOUNDATION | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232434-A1 | STAT3 INHIBITORS AND THEIR ANTICANCER USE | STAT3, STAT1, JAK1 | TDP1 1696/4885L3MBTL1 2458/4885KMT2A 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.