Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713979 | 0.93 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL10193228 | 0.93 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL17019860 | 0.89 | HSP90AA1 (0.32) | HSP90AA1TRPV1 | |
| Trifluoroacetic Acid SCHEMBL17019864 | 0.84 | SORD (0.34) | CYP11B2GPR6 | |
| Trifluoroacetic Acid SCHEMBL15808556 | 0.82 | SLC2A1 (0.35) | CYP11B2GPR6 | |
| Trifluoroacetic Acid SCHEMBL17019874 | 0.82 | CYP11B2 (0.34) | CYP11B2GPR6 | |
| Trifluoroacetic Acid SCHEMBL17019862 | 0.81 | TRPV1 (0.36) | TRPV1GPR6 | |
| Trifluoroacetic Acid SCHEMBL17019870 | 0.80 | — | — | |
| SCHEMBL515763 | 0.78 | — | — | |
| Trifluoroacetic Acid SCHEMBL16924600 | 0.78 | DPP4 (0.31) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115142-B2 | Heterocycle-substituted piperazino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-08-25 | — | — | US | disclosed |