Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516214 | 0.93 | SORD (0.39) | SORDAKT1CCNA2CDK2CCNA1 | |
| SCHEMBL18683880 | 0.93 | SORD (0.39) | SORDAKT1CCNA2CDK2CCNA1 | |
| Trifluoroacetic Acid SCHEMBL15808556 | 0.89 | SLC2A1 (0.35) | DPP4DPP8GPR6CYP11B2 | |
| SCHEMBL17019865 | 0.89 | SORD (0.32) | SORDKCNH2AKT1CYP2C9IDO1 | |
| Trifluoroacetic Acid SCHEMBL17019859 | 0.84 | HSP90AA1 (0.32) | GPR6CYP11B2 | |
| Trifluoroacetic Acid SCHEMBL17019874 | 0.84 | CYP11B2 (0.34) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| Trifluoroacetic Acid SCHEMBL15808591 | 0.84 | SORD (0.35) | SORDHRH4HRH3KCNH2CYP2D6 | |
| SCHEMBL7715595 | 0.81 | CCNA2 (0.33) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL194327 | 0.81 | CCNA2 (0.33) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| Trifluoroacetic Acid SCHEMBL17019870 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115142-B2 | Heterocycle-substituted piperazino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-08-25 | — | — | US | disclosed |