Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15808557 | 0.89 | ITGB3 (0.34) | ROCK2 | |
| Trifluoroacetic Acid SCHEMBL17019864 | 0.89 | SORD (0.34) | SORDCYP2C9IDO1KCNH2AKT1 | |
| SCHEMBL18683880 | 0.86 | SORD (0.39) | SORDAKT1 | |
| SCHEMBL516214 | 0.86 | SORD (0.39) | SORDAKT1 | |
| SCHEMBL17019860 | 0.84 | HSP90AA1 (0.32) | — | |
| SCHEMBL17019875 | 0.84 | GPR6 (0.31) | — | |
| SCHEMBL15808593 | 0.83 | SORD (0.32) | SORDGPR119 | |
| SCHEMBL17019871 | 0.82 | — | — | |
| SCHEMBL17019869 | 0.81 | — | — | |
| SCHEMBL975655 | 0.79 | SMN1; SMN2 (0.42) | CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115142-B2 | Heterocycle-substituted piperazino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-08-25 | — | — | US | disclosed |