Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30139044 | 0.92 | ACE (0.49) | PREPPRCPPIN1ACELMNA | |
| SCHEMBL30139010 | 0.92 | ACE (0.49) | PREPPRCPPIN1ACELMNA | |
| SCHEMBL17020437 | 0.91 | PIN1 (0.46) | ALDH1A1CYP3A4TSHRPRCPPIN1 | |
| SCHEMBL21467260 | 0.88 | ACE (0.52) | PREPPRCPPIN1ACELMNA | |
| SCHEMBL31217850 | 0.88 | ACE (0.52) | PREPPRCPPIN1ACELMNA | |
| SCHEMBL17015151 | 0.88 | ACE (0.52) | PREPPRCPPIN1ACELMNA | |
| SCHEMBL29759519 | 0.88 | ACE (0.52) | PREPPRCPPIN1ACELMNA | |
| SCHEMBL17020400 | 0.87 | PIN1 (0.49) | ALDH1A1CYP3A4TSHRPRCPPIN1 | |
| SCHEMBL13483341 | 0.87 | PREP (0.50) | PREPPRCPPIN1ACELMNA | |
| SCHEMBL13296586 | 0.87 | PREP (0.50) | PREPPRCPPIN1ACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | NEW YORK UNIVERSITY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | ALDH1A1 3/4885CYP3A4 1533/4885TSHR 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.