Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467286 | 0.83 | DAO (0.47) | NR1H2NR1H3RAB9ATSHRL3MBTL1 | |
| SCHEMBL4421581 | 0.81 | RAB9A (0.55) | SRCNR1H2NR1H3RAB9ATSHR | |
| SCHEMBL9514581 | 0.81 | DAO (0.59) | SRCNR1H2NR1H3RAB9ATSHR | |
| SCHEMBL2352393 | 0.81 | TYMP (0.54) | SRCNR1H2NR1H3RAB9ATSHR | |
| SCHEMBL14525877 | 0.79 | NR1H2 (0.66) | SRCNR1H2NR1H3RAB9ATSHR | |
| SCHEMBL8679771 | 0.78 | KDR (0.49) | TSHRDAOMCL1 | |
| SCHEMBL17022579 | 0.78 | POLB (0.52) | RAB9ATSHRL3MBTL1MEN1NPC1 | |
| SCHEMBL17856940 | 0.77 | RAB9A (0.48) | SRCNR1H2NR1H3RAB9ATSHR | |
| SCHEMBL6195893 | 0.76 | RAB9A (0.56) | SRCNR1H2NR1H3RAB9ATSHR | |
| SCHEMBL30804587 | 0.76 | RAB9A (0.56) | SRCNR1H2NR1H3RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910547-B1 | COMPOUND; TAUTOMER AND GEOMETRIC ISOMER THEREOF; SALT OF SAID COMPOUND, TAUTOMER, OR GEOMETRIC ISOMER; METHOD FOR MANUFACTURING SAID COMPOUND, TAUTOMER, ISOMER, OR SALT; ANTIMICROBIAL AGENT; AND ANTI-INFECTIVE DRUG | UNIV OKAYAMA (JP) | 2017-06-14 | — | — | EP | disclosed |
| US-9512075-B2 | Compound; tautomer and geometric isomer thereof; salt of said compound, tautomer, or geometric isomer; method for manufacturing said compound, tautomer, isomer, or salt; antimicrobial agent; and anti-infective drug | OKAYAMA UNIVERSITY (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20150291523-A1 | COMPOUND; TAUTOMER AND GEOMETRIC ISOMER THEREOF; SALT OF SAID COMPOUND, TAUTOMER, OR GEOMETRIC ISOMER; METHOD FOR MANUFACTURING SAID COMPOUND, TAUTOMER, ISOMER, OR SALT; ANTIMICROBIAL AGENT; AND ANTI-INFECTIVE DRUG | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2015-10-15 | — | — | US | disclosed |
| EP-2910547-A1 | COMPOUND; TAUTOMER AND GEOMETRIC ISOMER THEREOF; SALT OF SAID COMPOUND, TAUTOMER, OR GEOMETRIC ISOMER; METHOD FOR MANUFACTURING SAID COMPOUND, TAUTOMER, ISOMER, OR SALT; ANTIMICROBIAL AGENT; AND ANTI-INFECTIVE DRUG | Okayama University (JP) | 2015-08-26 | — | — | EP | disclosed |
| CN-1003855-B | Process for preparing 1, 3-disubstituted 2-oxindoles | 美国辉瑞有限公司 | 1989-04-12 | — | — | CN | disclosed |
| CN-85101795-A | With 1, the two 2-oxyindoles that replace of 3-prepare pain killer and antiphlogistic | — | 1987-04-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291523-A1 | COMPOUND; TAUTOMER AND GEOMETRIC ISOMER THEREOF; SALT OF SAID COMPOUND, TAUTOMER, OR GEOMETRIC ISOMER; METHOD FOR MANUFACTURING SAID COMPOUND, TAUTOMER, ISOMER, OR SALT; ANTIMICROBIAL AGENT; AND ANTI-INFECTIVE DRUG | FURIN, ACE, SHARPIN | SRC 2158/4885NR1H2 1391/4885NR1H3 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.