SCHEMBL9514581

SCHEMBL9514581

O=C(O)c1cc2ccccc2n1C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.59
MCL1 Q07820 1/20 0.57
TSHR P16473 2/20 0.56
ALDH1A1 P00352 2/20 0.56
NOD2 Q9HC29 1/20 0.55
NOD1 Q9Y239 1/20 0.55
CCR2 P41597 2/20 0.51
PLA2G10 O15496 2/20 0.49
RAB9A P51151 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
P2RX4 Q99571 1/20 0.49
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
SRC P12931 1/20 0.47
NR1H2 P55055 2/20 0.47
NR1H3 Q13133 1/20 0.47
AGTR1 P30556 2/20 0.46
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29780995 0.84 DAO (0.65) DAOMCL1TSHRALDH1A1NOD2
SCHEMBL3638561 0.84 DAO (0.65) DAOMCL1TSHRALDH1A1NOD2
SCHEMBL3969204 0.83 PARP1 (0.49) DAOMCL1ALDH1A1NOD2NOD1
SCHEMBL17022686 0.81 SRC (0.53) DAOMCL1TSHRNOD2NOD1
SCHEMBL4222282 0.81 MCL1 (0.64) DAOMCL1TSHRALDH1A1NOD2
SCHEMBL2352393 0.79 TYMP (0.54) MCL1TSHRALDH1A1NOD2NOD1
SCHEMBL4421581 0.79 RAB9A (0.55) DAOMCL1TSHRALDH1A1NOD2
SCHEMBL14398966 0.78 MCL1 (0.60) DAOMCL1TSHRALDH1A1NOD2
SCHEMBL14525877 0.78 NR1H2 (0.66) TSHRALDH1A1RAB9AL3MBTL1P2RX4
SCHEMBL6988076 0.77 MCL1 (0.58) DAOMCL1TSHRALDH1A1NOD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
EP-0249885-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-01-02 EP disclosed
EP-0234540-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-10-16 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
US-4794101-A MIXTURE OF PHTHALIDE DYE, FLUORAN COMPOUND AND POLYVALENT METAL SALT OF AN AROMATIC CARBOXYLIC ACID KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-12-27 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed
US-4731353-A METAL SALT OF INDOLE-2-CARBOXYLIC ACID COLOR DEVELOPER KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1988-03-15 US disclosed
EP-0249885-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-12-23 EP disclosed
EP-0234540-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-09-02 EP disclosed
EP-0126598-A1 Benzoyl indolecarboxylates KOWA COMPANY, LTD. (JP) 1984-11-28 EP disclosed