Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15639637 | 0.79 | MEN1 (0.34) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL17023418 | 0.79 | ADORA2A (0.41) | ADORA2ANOS3NOS1NOS2PI4KA | |
| SCHEMBL17023407 | 0.79 | EPHX2 (0.47) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL29571972 | 0.79 | MEN1 (0.33) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15639083 | 0.79 | MEN1 (0.33) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1812562 | 0.77 | NOTUM (0.39) | ALDH1A1L3MBTL1KDM4EHDAC9MPI | |
| SCHEMBL15638638 | 0.76 | KDM4E (0.43) | ALDH1A1KDM4EADORA2AMAPTDRD4 | |
| SCHEMBL15639935 | 0.75 | L3MBTL1 (0.36) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1807312 | 0.74 | NAPRT (0.40) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL15639432 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548854-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2023-01-10 | — | — | US | disclosed |
| US-11332448-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2022-05-17 | — | — | US | disclosed |
| CN-113243374-B | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-113243374-A | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-108477173-B | Heterocyclic compounds as pesticides | 拜耳农作物科学股份公司 | 2021-07-02 | — | — | CN | disclosed |
| US-10961201-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2021-03-30 | — | — | US | disclosed |
| US-20210053924-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-02-25 | — | — | US | disclosed |
| US-20210017136-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-01-21 | — | — | US | disclosed |
| US-10689348-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2020-06-23 | — | — | US | disclosed |
| US-10435374-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2019-10-08 | — | — | US | disclosed |
| WO-2018107056-A1 | 1,3-SUBSTITUED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACIC LEVELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-06-14 | — | — | WO | disclosed |
| US-9802899-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-10-26 | — | — | US | disclosed |
| EP-2903440-B1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROLLING AGENTS | BAYER CROPSCIENCE AG (DE) | 2017-09-06 | — | — | EP | disclosed |
| EP-2999338-B1 | KNOWN AND NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-12 | — | — | EP | disclosed |
| US-20150239847-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10435374-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-10961201-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-10689348-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-11548854-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-20210053924-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-11332448-B2 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-20210017136-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
| US-20150239847-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | ALDH1A1 2740/4885MEN1 2069/4885KMT2A 2247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.