SCHEMBL17023940

SCHEMBL17023940

OC1COC1C1OCC1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 1.00
LMNA P02545 1/20 1.00
MAPT P10636 1/20 0.48
BCHE P06276 1/20 0.33
FUCA1 P04066 1/20 0.30
GBA1 P04062 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isosorbide SCHEMBL9882796 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL6298736 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL6105354 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL196402 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL346855 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL24465084 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL15440712 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL244589 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL1918479 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1
Isosorbide SCHEMBL13938288 1.00 THRB (1.00) THRBLMNAMAPTBCHEFUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428888-B Aqueous polyurethane-polyacrylate dispersions 科思创德国股份有限公司 2020-10-16 CN disclosed
US-10066122-B2 Formable film BENECKE-KALIKO AG (DE) 2018-09-04 US disclosed
US-20180118971-A1 AQUEOUS POLYURETHANE-POLYACRYLATE DISPERSIONS COVESTRO DEUTSCHLAND AG (DE) 2018-05-03 US disclosed
US-20150240116-A1 DEFORMABLE FILM BENECKE-KALIKO AG (DE) 2015-08-27 US disclosed