SCHEMBL1702396

SCHEMBL1702396

CC(C)(C)c1ccc(OC(c2ccc(C(C)(C)C)cc2C(C)(C)C)(c2ccc(C(C)(C)C)cc2C(C)(C)C)C(CO)(CO)CO)c(C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.35
APEX1 P27695 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 5/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPSR1 Q6W5P4 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPK1 P28482 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27203702 0.96 TRPV1 (0.35) CYP2C19APEX1TRPV1KDM4EALDH1A1
SCHEMBL17707252 0.96 TRPV1 (0.35) CYP2C19APEX1TRPV1KDM4EALDH1A1
SCHEMBL17707251 0.87 TRPV1 (0.33) CYP2C19APEX1TRPV1NPSR1MAPK1
SCHEMBL4215102 0.81 ALDH1A1 (0.33) TRPV1ALDH1A1ALOX15HSD17B10HPGD
SCHEMBL8374079 0.79 ALDH1A1 (0.32) CYP2C19ALDH1A1ALOX15HSD17B10HPGD
SCHEMBL10715127 0.79 TRPV1 (0.31) CYP2C19APEX1TRPV1L3MBTL1
SCHEMBL28895657 0.76 ALDH1A1 (0.38) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL29556111 0.76 ALDH1A1 (0.38) CYP2C19ALDH1A1ALOX15HSD17B10HPGD
SCHEMBL29978779 0.74 ALDH1A1 (0.37) CYP2C19ALDH1A1ALOX15HSD17B10HPGD
SCHEMBL26105004 0.74 TDP1 (0.43) CYP2C19KDM4EALDH1A1HSD17B10CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433067-B Preparation method of beta-isophorone 万华化学集团股份有限公司 2023-12-19 CN claimed
CN-115433067-A Preparation method of beta-isophorone 万华化学集团股份有限公司 2022-12-06 CN claimed
US-5278209-A Oxidation resistance B.F. GOODRICH COMPANY, THE 1994-01-11 US claimed
EP-0548293-A1 THERMOOXIDATIVE STABILIZATION OF POLYOLEFINS WITH AN OXO-PIPERAZINYL-TRIAZINE AND A PHOSPHOROUS ACID ESTER THE B.F. GOODRICH COMPANY (US) 1993-06-30 EP claimed
WO-1992004404-A2 THERMOOXIDATIVE STABILIZATION OF POLYOLEFINS WITH AN OXO-PIPERAZINYL-TRIAZINE AND A PHOSPHOROUS ACID ESTER THE B.F. GOODRICH COMPANY (US) 1992-03-19 WO claimed
US-12595364-B2 Thermoplastic resin composition for air intake hose with improved heat resistance and molded article comprising same HYUNDAI MOTOR COMPANY (KR) 2026-04-07 US disclosed
US-20240228772-A9 THERMOPLASTIC RESIN COMPOSITION FOR AIR INTAKE HOSE WITH IMPROVED HEAT RESISTANCE AND MOLDED ARTICLE COMPRISING SAME HYUNDAI MOTOR COMPANY (KR) 2024-07-11 US disclosed
US-20240132717-A1 THERMOPLASTIC RESIN COMPOSITION FOR AIR INTAKE HOSE WITH IMPROVED HEAT RESISTANCE AND MOLDED ARTICLE COMPRISING SAME HYUNDAI MOTOR CO LTD (KR) 2024-04-25 US disclosed
CN-111065717-B Lubricant composition and rolling bearing sealed with the same 日本精工株式会社 2024-02-20 CN disclosed
CN-115433067-B Preparation method of beta-isophorone 万华化学集团股份有限公司 2023-12-19 CN disclosed
CN-113906093-B Polycarbonate resin composition 三菱工程塑料株式会社 2023-06-16 CN disclosed
CN-115433067-A Preparation method of beta-isophorone 万华化学集团股份有限公司 2022-12-06 CN disclosed
US-5627299-A REACTION OF ALCOHOL WITH PHOSPHOROUS OXYCHLORIDE TO FORM PHOSPHATES DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-05-06 US disclosed
EP-0735039-A2 A process for preparing tribromoneopentyl chloroalkyl phosphates DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 1996-10-02 EP disclosed
EP-0376289-B1 Polycarbonate resin composition for radiation sterilization MITSUBISHI GAS CHEMICAL CO (JP) 1995-11-29 EP disclosed
US-5278209-A Oxidation resistance B.F. GOODRICH COMPANY, THE 1994-01-11 US disclosed
EP-0548293-A1 THERMOOXIDATIVE STABILIZATION OF POLYOLEFINS WITH AN OXO-PIPERAZINYL-TRIAZINE AND A PHOSPHOROUS ACID ESTER THE B.F. GOODRICH COMPANY (US) 1993-06-30 EP disclosed
US-5118726-A From a halogenated bisphenol, with a release agent and a polyoxyalkylene compound to prevent yellowing; medical appliances MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 1992-06-02 US disclosed
WO-1992004404-A2 THERMOOXIDATIVE STABILIZATION OF POLYOLEFINS WITH AN OXO-PIPERAZINYL-TRIAZINE AND A PHOSPHOROUS ACID ESTER THE B.F. GOODRICH COMPANY (US) 1992-03-19 WO disclosed
EP-0376289-A2 Polycarbonate resin composition for radiation sterilization MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1990-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595364-B2 Thermoplastic resin composition for air intake hose with improved heat resistance and molded article comprising same HSPE1, HSPA4L, HAO2 CYP2C19 1729/4885APEX1 940/4885TRPV1 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.