Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17024411 | 1.00 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1HIF1AGPR88TSHR | |
| SCHEMBL17024413 | 0.91 | TSHR (0.36) | HIF1ATSHRMAPK1ADRB2 | |
| SCHEMBL27795612 | 0.91 | TSHR (0.36) | HIF1ATSHRMAPK1ADRB2 | |
| SCHEMBL17024415 | 0.91 | TSHR (0.36) | HIF1ATSHRMAPK1ADRB2 | |
| SCHEMBL4568809 | 0.83 | HIF1A (0.44) | CYSLTR2CYSLTR1HIF1ATSHRMAPK1 | |
| SCHEMBL4568963 | 0.83 | HIF1A (0.44) | CYSLTR2CYSLTR1HIF1ATSHRMAPK1 | |
| SCHEMBL4568796 | 0.83 | HIF1A (0.44) | CYSLTR2CYSLTR1HIF1ATSHRMAPK1 | |
| SCHEMBL27795714 | 0.83 | GGPS1 (0.50) | TSHR | |
| SCHEMBL27795610 | 0.83 | GGPS1 (0.50) | TSHR | |
| SCHEMBL2204823 | 0.81 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1HIF1ATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239836-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239836-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYSLTR2 456/4885CYSLTR1 417/4885HIF1A 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.