Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17024415 | 1.00 | TSHR (0.36) | TSHRMAPK1HIF1AADRB2KDM4E | |
| SCHEMBL27795612 | 1.00 | TSHR (0.36) | TSHRMAPK1HIF1AADRB2KDM4E | |
| SCHEMBL17024418 | 0.91 | CYSLTR2 (0.39) | TSHRMAPK1HIF1AADRB2 | |
| SCHEMBL17024411 | 0.91 | CYSLTR2 (0.39) | TSHRMAPK1HIF1AADRB2 | |
| SCHEMBL4568810 | 0.83 | TSHR (0.44) | TSHRMAPK1HIF1AADRB2KDM4E | |
| SCHEMBL4568962 | 0.83 | TSHR (0.44) | TSHRMAPK1HIF1AADRB2KDM4E | |
| SCHEMBL4568795 | 0.83 | TSHR (0.44) | TSHRMAPK1HIF1AADRB2KDM4E | |
| SCHEMBL27795610 | 0.82 | GGPS1 (0.50) | TSHR | |
| SCHEMBL27795714 | 0.82 | GGPS1 (0.50) | TSHR | |
| SCHEMBL27996080 | 0.80 | LMNA (0.40) | TSHRMAPK1HIF1AADRB2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239836-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2015-08-27 | — | — | US | disclosed |
| CN-103553945-B | Alkoxy compounds for disease treatment | ACUCELA INC | 2015-01-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239836-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | TSHR 2964/4885MAPK1 2505/4885HIF1A 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.