Tembotrione

Tembotrione

SCHEMBL170254

CCOC(=O)C1=NOC(c2ccccc2)(c2ccccc2)C1.CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1.CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1COCC(F)(F)F

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.30
ERBB2 P04626 1/20 0.30
PDGFRB P09619 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tembotrione SCHEMBL170539 0.88
Tembotrione SCHEMBL2418746 0.88
Tembotrione SCHEMBL170587 0.88 KDM4E (0.32)
Tembotrione SCHEMBL167368 0.85
Tembotrione SCHEMBL168161 0.84
Tembotrione SCHEMBL17927095 0.83 HPD (0.39)
Sulcotrione SCHEMBL14655388 0.80 LMNA (0.35)
Tembotrione SCHEMBL170538 0.78
Tembotrione SCHEMBL3225813 0.76 HPD (0.38)
Tembotrione SCHEMBL116424 0.76 HPD (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673814-B2 Synergistic combinations which are compatible with cultivated plants and which comprise herbicides selected from the group consisting of benzoylcyclohexanediones for use in rice crops BAYER CROPSCIENCE AG (DE) 2014-03-18 US disclosed
US-20120058894-A1 SYNERGISTIC COMBINATIONS WHICH ARE COMPATIBLE WITH CULTIVATED PLANTS AND WHICH COMPRISE HERBICIDES SELECTED FROM THE GROUP CONSISTING OF BENZOYLCYCLOHEXANEDIONES FOR USE IN RICE CROPS BAYER CROPSCIENCE AG (DE) 2012-03-08 US disclosed
US-20080318786-A1 SYNERGISTIC COMBINATIONS WHICH ARE COMPATIBLE WITH CULTIVATED PLANTS AND WHICH COMPRISE HERBICIDES SELECTED FROM THE GROUP CONSISTING OF BENZOYLCYCLOHEXANEDIONES FOR USE IN RICE CROPS BAYER CROPSCIENCE AG (DE) 2008-12-25 US disclosed