Tembotrione

Tembotrione

SCHEMBL170539

CCOC(=O)C1=NOC(c2ccccc2)(c2ccccc2)C1.CS(=O)(=O)c1ccc(C(=O)C2=C(Sc3ccccc3)C3CCC(C3)C2=O)c(Cl)c1.CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(Cl)c1COCC(F)(F)F

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tembotrione SCHEMBL170254 0.88 EGFR (0.30)
Tembotrione SCHEMBL170549 0.88 NR1I2 (0.30)
Tembotrione SCHEMBL170587 0.80 KDM4E (0.32)
Tembotrione SCHEMBL2418746 0.79
Tembotrione SCHEMBL168161 0.77
Tembotrione SCHEMBL167368 0.76
Tembotrione SCHEMBL17927095 0.73 HPD (0.39)
Mesotrione SCHEMBL17927166 0.70 HPD (0.40)
Tembotrione SCHEMBL170538 0.70
Sulcotrione SCHEMBL14655388 0.70 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673814-B2 Synergistic combinations which are compatible with cultivated plants and which comprise herbicides selected from the group consisting of benzoylcyclohexanediones for use in rice crops BAYER CROPSCIENCE AG (DE) 2014-03-18 US disclosed
US-20120058894-A1 SYNERGISTIC COMBINATIONS WHICH ARE COMPATIBLE WITH CULTIVATED PLANTS AND WHICH COMPRISE HERBICIDES SELECTED FROM THE GROUP CONSISTING OF BENZOYLCYCLOHEXANEDIONES FOR USE IN RICE CROPS BAYER CROPSCIENCE AG (DE) 2012-03-08 US disclosed
US-20080318786-A1 SYNERGISTIC COMBINATIONS WHICH ARE COMPATIBLE WITH CULTIVATED PLANTS AND WHICH COMPRISE HERBICIDES SELECTED FROM THE GROUP CONSISTING OF BENZOYLCYCLOHEXANEDIONES FOR USE IN RICE CROPS BAYER CROPSCIENCE AG (DE) 2008-12-25 US disclosed