SCHEMBL17026040

SCHEMBL17026040

CC1CN(c2ccc(-c3ccc(-c4nnn(C)n4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.82

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 12/20 0.82
MAOB P27338 2/20 0.82
CALML3 P27482 5/20 0.47
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
CYP3A4 P08684 1/20 0.45
GRM2 Q14416 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1380845 1.00 MAOA (0.82) MAOAMAOBCALML3CYP2C19CYP2C9
Dimethylamine SCHEMBL3060516 0.97 MAOA (0.78) MAOAMAOBCALML3CYP2C19CYP2C9
Phosphoric Acid SCHEMBL29016318 0.96 MAOA (0.77) MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL1380839 0.92 MAOA (0.81) MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL17026039 0.92 MAOA (0.81) MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL28725118 0.91 MAOA (0.79) MAOAMAOBCALML3CYP2C19CYP2C9
SCHEMBL28725115 0.91 MAOA (0.79) MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL3807996 0.90 MAOA (1.00) MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL440398 0.90 MAOA (1.00) MAOAMAOBCALML3CYP2C19CYP2C9
Tedizolid SCHEMBL31385281 0.90 MAOA (1.00) MAOAMAOBCALML3CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107923-A1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION Micurx Pharmaceuticals, Inc. (US) 2016-12-28 EP claimed
US-9382276-B2 Water-soluble O-carbonyl phosphoramidate prodrugs for therapeutic administration MICURX PHARMACEUTICALS, INC. (US) 2016-07-05 US claimed
US-20150239922-A1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) 2015-08-27 US claimed
WO-2015127316-A1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION MICURX PHARMACEUTICALS, INC. (US) 2015-08-27 WO claimed
EP-3107923-B1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION SHANGHAI MICURX PHARMACEUTICAL CO LTD (CN) 2021-11-03 EP disclosed
EP-3107923-A1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION Micurx Pharmaceuticals, Inc. (US) 2016-12-28 EP disclosed
US-9382276-B2 Water-soluble O-carbonyl phosphoramidate prodrugs for therapeutic administration MICURX PHARMACEUTICALS, INC. (US) 2016-07-05 US disclosed
WO-2015127316-A1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION MICURX PHARMACEUTICALS, INC. (US) 2015-08-27 WO disclosed
US-20150239922-A1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION SHANGHAI MICURX PHARMACEUTICAL CO. LTD. (CN) 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150239922-A1 WATER-SOLUBLE O-CARBONYL PHOSPHORAMIDATE PRODRUGS FOR THERAPEUTIC ADMINISTRATION DPYD, SI, NUDT1 MAOA 2019/4885MAOB 1186/4885CALML3 4085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.