Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026725 | 0.94 | ALDH1A1 (0.54) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13412905 | 0.88 | CA5A (0.57) | ALDH1A1CYP1A2CYP2C19GAATSHR | |
| SCHEMBL1883666 | 0.87 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL2525777 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| Bromide SCHEMBL10998875 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3054967 | 0.83 | CA5A (0.54) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL31661761 | 0.83 | CA5A (0.54) | ALDH1A1GAATSHRNFKB1TDP1 | |
| SCHEMBL8051796 | 0.82 | THRA (0.47) | ALDH1A1MAPTPTGDR2KDM4ELMNA | |
| SCHEMBL17316379 | 0.82 | PTGDR2 (0.42) | ALDH1A1PTGDR2RXRARXRBRXRG | |
| SCHEMBL13412908 | 0.82 | THRA (0.54) | ALDH1A1PTGDR2GAATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110427-A1 | COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE | Urigen Pharmaceuticals, Inc. (US) | 2017-01-04 | — | — | EP | claimed |
| WO-2015127416-A1 | COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE | URIGEN PHARMACEUTICALS, INC. (US) | 2015-08-27 | — | — | WO | claimed |