Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026908 | 0.87 | KIF11 (0.52) | KIF11MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL17026971 | 0.74 | MEN1 (0.51) | KIF11MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL17026924 | 0.74 | ASIC3 (0.45) | KIF11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL17027128 | 0.72 | ALOX5 (0.49) | KIF11MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL17026987 | 0.72 | MEN1 (0.46) | KIF11MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL17027263 | 0.72 | MEN1 (0.45) | KIF11MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL17027039 | 0.70 | MEN1 (0.43) | KIF11MEN1KMT2ACCNB2CDK1 | |
| SCHEMBL10253400 | 0.68 | KIF11 (1.00) | KIF11MEN1KMT2AKDM4ECHUK | |
| SCHEMBL412032 | 0.66 | KIF11 (0.81) | KIF11MEN1KMT2AKDM4ECHUK | |
| SCHEMBL29507666 | 0.66 | KIF11 (0.81) | KIF11MEN1KMT2AKDM4ECHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107910-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015124868-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2015-08-27 | — | — | WO | disclosed |