Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327114 | 0.83 | TBXAS1 (0.56) | TBXAS1MEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL3184412 | 0.83 | TBXAS1 (0.52) | TBXAS1MEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL27220751 | 0.81 | HTR2A (0.59) | TBXAS1ALDH1A1CYP1A2HTR2A | |
| SCHEMBL27220749 | 0.81 | HTR2A (0.59) | TBXAS1ALDH1A1CYP1A2HTR2A | |
| SCHEMBL2537034 | 0.81 | HTR2A (0.65) | TBXAS1MEN1CYP1A2KMT2AHTR2A | |
| SCHEMBL13715393 | 0.81 | TBXAS1 (0.53) | TBXAS1MEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL6029337 | 0.80 | CSNK2A1 (0.53) | TBXAS1MEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL6031020 | 0.80 | MEN1 (0.55) | TBXAS1MEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL2386812 | 0.78 | ALDH1A1 (0.58) | TBXAS1MEN1ALDH1A1CYP1A2HPGD | |
| SCHEMBL6031147 | 0.77 | ICMT (0.63) | TBXAS1MEN1ALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107910-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015124868-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2015-08-27 | — | — | WO | disclosed |