Bronopol

Bronopol

SCHEMBL1702852

C[N+](=O)[O-].O=[N+]([O-])C(Br)(CO)CO

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.85
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bronopol SCHEMBL7069554 0.92 LMNA (1.00) LMNAALDH1A1TDP1TSHR
Bronopol SCHEMBL23260 0.92
Bronopol SCHEMBL31490721 0.90 LMNA (0.94) LMNAALDH1A1TDP1TSHR
Bronopol SCHEMBL5076392 0.83 LMNA (0.81) LMNA
Bronopol SCHEMBL28857973 0.83 LMNA (0.81) LMNA
SCHEMBL1703576 0.83
Bronopol SCHEMBL31672719 0.81
Bronopol SCHEMBL7865473 0.81 LMNA (0.77) LMNA
SCHEMBL15295432 0.80
Bronopol SCHEMBL2680265 0.79 LMNA (0.65) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440047-B1 BROMINATED NITROALKANOL COMPOSITIONS AND THEIR USE AS BIOCIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2013-05-08 EP disclosed
EP-2440047-A1 BROMINATED NITROALKANOL COMPOSITIONS AND THEIR USE AS BIOCIDES Dow Global Technologies LLC (US) 2012-04-18 EP disclosed
WO-2010144511-A1 BROMINATED NITROALKANOL COMPOSITIONS AND THEIR USE AS BIOCIDES DOW GLOBAL TECHNOLOGIES INC. (US) 2010-12-16 WO disclosed