Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376975 | 0.85 | — | — | |
| Bronopol SCHEMBL23260 | 0.81 | — | — | |
| Bronopol SCHEMBL7069554 | 0.81 | LMNA (1.00) | LMNAALDH1A1 | |
| Bronopol SCHEMBL1702852 | 0.79 | LMNA (0.85) | LMNAALDH1A1 | |
| Bronopol SCHEMBL31490721 | 0.79 | LMNA (0.94) | LMNAALDH1A1 | |
| Bronopol SCHEMBL5076392 | 0.73 | LMNA (0.81) | LMNA | |
| Bronopol SCHEMBL28857973 | 0.73 | LMNA (0.81) | LMNA | |
| SCHEMBL1703576 | 0.73 | — | — | |
| Bronopol SCHEMBL31672719 | 0.71 | — | — | |
| Bronopol SCHEMBL7865473 | 0.71 | LMNA (0.77) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120114728-A1 | BIODELIVERY SYSTEMS | GENERAL ELECTRIC COMPANY | 2012-05-10 | — | — | US | disclosed |
| US-20100239626-A1 | PROPANEDIOL DELIVERY SYSTEMS | GENERAL ELECTRIC COMPANY | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114728-A1 | BIODELIVERY SYSTEMS | LIPA, MGLL, LIPG | LMNA 1648/4885ALDH1A1 4359/4885KDM4E 3444/4885 |
| US-20100239626-A1 | PROPANEDIOL DELIVERY SYSTEMS | PLD2, PLD3, MGLL | LMNA 1272/4885ALDH1A1 1948/4885KDM4E 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.