Bronopol

Bronopol

SCHEMBL7069554

O=[N+]([O-])C(Br)(CO)CO.O=[N+]([O-])C(Br)(CO)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 2/20 0.35
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bronopol SCHEMBL23260 1.00
Bronopol SCHEMBL31490721 0.97 LMNA (0.94) LMNAALDH1A1TDP1TSHRCA5A
Bronopol SCHEMBL1702852 0.92 LMNA (0.85) LMNAALDH1A1TDP1TSHR
Bronopol SCHEMBL5076392 0.90 LMNA (0.81) LMNA
Bronopol SCHEMBL28857973 0.90 LMNA (0.81) LMNA
Bronopol SCHEMBL31672719 0.88
Bronopol SCHEMBL7865473 0.88 LMNA (0.77) LMNA
SCHEMBL15295432 0.87
SCHEMBL1703576 0.85
Bronopol SCHEMBL10453156 0.84 LMNA (0.71) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6524858-B1 Use of an organic dye in the reagent solution for staining the nucleic acid of reticulocytes, including reticulated platelets, and white blood cells in the sample BAYER CORPORATION 2003-02-25 US claimed
EP-3927799-A1 ALPHA-OLEFIN SULFONATE-CONTAINING DISHWASHING DETERGENTS Henkel AG & Co. KGaA (DE) 2021-12-29 EP disclosed
EP-3759205-A1 ISOTHIAZINONE-FREE PRESERVATION OF CLEANING AGENTS Henkel AG & Co. KGaA (DE) 2021-01-06 EP disclosed
WO-2020239543-A1 IMPROVED SOLUBILITY BY MEANS OF A SPECIFIC SURFACTANT MIXTURE HENKEL AG & CO. KGAA (DE) 2020-12-03 WO disclosed
EP-3510867-A1 ANTIMICROBIAL POLYMER BASF SE (DE) 2019-07-17 EP disclosed
US-20190133125-A1 ANTIMICROBIAL POLYMER BASF SE (DE) 2019-05-09 US disclosed
EP-3433351-A1 CLEANING AGENT CONTAINING PROTEASE AND AMYLASE Henkel AG & Co. KGaA (DE) 2019-01-30 EP disclosed
EP-3430112-A1 GRANULATE COMPRISING AN INORGANIC SOLID CARRIER WITH AT LEAST ONE BIOSURFACTANT CONTAINED THEREON Evonik Degussa GmbH (DE) 2019-01-23 EP disclosed
EP-3334280-A1 ANTIMICROBIAL POLYMER BASF SE (DE) 2018-06-20 EP disclosed
EP-3325595-A1 DETERGENT OR CLEANING AGENT WITH AT LEAST TWO PHASES Henkel AG & Co. KGaA (DE) 2018-05-30 EP disclosed
EP-3041352-A1 CLEANING LIQUID Scoones, Robert (GB) 2016-07-13 EP disclosed
WO-2015028806-A1 CLEANING LIQUID SCOONES ROBERT (GB) 2015-03-05 WO disclosed
EP-2579972-A1 METHOD FOR PREPARING A NON-IONIC SURFACTANT STABLE PERSONAL CARE DISPERSION The Procter and Gamble Company (US) 2013-04-17 EP disclosed
WO-2003054125-A1 CLEANING AGENT COMPRISING MICROCAPSULES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-07-03 WO disclosed
US-6524858-B1 Use of an organic dye in the reagent solution for staining the nucleic acid of reticulocytes, including reticulated platelets, and white blood cells in the sample BAYER CORPORATION 2003-02-25 US disclosed
US-6114173-A ACCURATE LIGHT SCATTER/ABSORPTION FLOW CYTOMETRY PROCESS USING AUTOMATED HEMATOLOGY ANALYZER WITH NO SAMPLE PREPARATION TIME; USES AQUEOUS REAGENT INCLUDING CATIONIC DYE, ZWITTERIONIC SURFACTANT AND BUFFER BAYER CORPORATION (US) 2000-09-05 US disclosed
US-6001339-A NON-RIGID CROSSLINKED SILICONE POLYMER, DIMETHICONOL; CATIONIC POLYMER; SPECIFIC NONIONIC SURFACTANTS COMBINED WITH AMPHOTERIC SURFACTANTS SUCH AS COCAMIDOPROPYL BETAINE; AN ALCOHOL; AND PROPELLANT; BALANCE OF CONDITIONING AND STYLING HELENE CURTIS, INC. (US) 1999-12-14 US disclosed
US-5888752-A ANTIDEPOSIT AGENTS BAYER CORPORATION (US) 1999-03-30 US disclosed
EP-0869347-A2 Method and reagent for identification of reticulocytes, erythrocytes and platelets Bayer Corporation (US) 1998-10-07 EP disclosed
WO-1998002740-A1 METHOD AND COMPOSITION FOR PRESERVING ANTIGENS AND NUCLEIC ACIDS AND PROCESS FOR UTILIZING CYTOLOGICAL MATERIAL PRODUCED BY SAME STRECK LABORATORIES, INC. (US) 1998-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190133125-A1 ANTIMICROBIAL POLYMER C9, PM20D2, DDC LMNA 1870/4885ALDH1A1 2897/4885TDP1 2714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.