SCHEMBL17028635

SCHEMBL17028635

CCC(CC(=O)O)c1ccc(OCc2cccnc2-c2ccc(C3(C#N)CC3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 10/20 0.68
FFAR1 O14842 9/20 0.46
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
ACACB O00763 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17028633 0.83 FFAR4 (0.73) FFAR4FFAR1ACACB
SCHEMBL17028620 0.81 FFAR4 (1.00) FFAR4FFAR1
SCHEMBL17028634 0.78 FFAR4 (0.79) FFAR4FFAR1
SCHEMBL17028705 0.65 FFAR1 (0.51) FFAR4FFAR1
SCHEMBL17028529 0.63 FFAR4 (1.00) FFAR4
SCHEMBL6208176 0.63 MAOB (0.58) FFAR4
SCHEMBL13350425 0.63 FFAR1 (0.64) FFAR1
SCHEMBL13564577 0.63 FFAR1 (0.55) FFAR1
SCHEMBL13118253 0.63 FFAR1 (1.00) FFAR1
SCHEMBL4355309 0.62 POLB (0.54) FFAR4ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107901-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2016-12-28 EP disclosed
WO-2015125085-A1 COMPOUNDS FOR USE AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2015-08-27 WO disclosed