Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 9/20 | 0.52 |
| ▸ | GUCY1A2 | P33402 | 9/20 | 0.52 |
| ▸ | GUCY1A1 | Q02108 | 9/20 | 0.52 |
| ▸ | GUCY1B1 | Q02153 | 9/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ATP4A | P20648 | 2/20 | 0.47 |
| ▸ | ATP4B | P51164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403246 | 0.91 | GUCY1B2 (0.58) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL15630797 | 0.82 | GUCY1B2 (0.62) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL17028950 | 0.81 | GUCY1B2 (0.54) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL16402699 | 0.80 | GUCY1B2 (0.57) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL17028936 | 0.79 | GUCY1B2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL17028939 | 0.79 | GUCY1B2 (0.53) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL15630778 | 0.79 | SMN1; SMN2 (0.60) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL17028948 | 0.79 | ATP4A (0.72) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16402969 | 0.77 | GUCY1B2 (0.54) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL17717804 | 0.77 | GUCY1B2 (0.52) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107920-B1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | Bayer Pharma AG (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-3107920-B1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | Bayer Pharma AG (DE) | 2017-10-18 | — | — | EP | disclosed |
| US-9688699-B2 | 3-(pyrimidine-2-yl)imidazo[1,2-a]pyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688699-B2 | 3-(pyrimidine-2-yl)imidazo[1,2-a]pyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| US-9688699-B2 | 3-(pyrimidine-2-yl)imidazo[1,2-a]pyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-27 | — | — | US | disclosed |
| EP-3107920-A1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2016-12-28 | — | — | EP | disclosed |
| US-20160347770-A1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-01 | — | — | US | disclosed |
| US-20160347770-A1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-01 | — | — | US | disclosed |
| US-20160347770-A1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-01 | — | — | US | disclosed |
| WO-2015124544-A1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-08-27 | — | — | WO | disclosed |
| WO-2015124544-A1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160347770-A1 | 3-(PYRIMIDINE-2-YL)IMIDAZO[1,2-A]PYRIDINES | TPMT, PNPO, PDXK | GUCY1B2 1123/4885GUCY1A2 676/4885GUCY1A1 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.