SCHEMBL17029378

SCHEMBL17029378

CCCC(=O)c1cc(O)c(I)cc1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.72
HSD17B10 Q99714 2/20 0.72
TSHR P16473 2/20 0.72
ALDH1A1 P00352 1/20 0.72
HPGD P15428 1/20 0.72
RECQL P46063 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
HMGCR P04035 2/20 0.46
HTT P42858 2/20 0.44
HSD17B3 P37058 1/20 0.40
KDM4E B2RXH2 3/20 0.38
HSP90AB1 P08238 1/20 0.38
TCF4 P15884 1/20 0.38
CTNNB1 P35222 1/20 0.38
FASN P49327 1/20 0.37
LMNA P02545 3/20 0.36
ESR1 P03372 1/20 0.36
FFAR1 O14842 1/20 0.35
PLA2G2A P14555 1/20 0.35
PLA2G5 P39877 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29430367 0.84 ALOX15 (1.00) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL43001 0.84 ALOX15 (1.00) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL946114 0.73 ALDH1A1 (0.66) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL11874178 0.73 ALDH1A1 (0.78) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL3662473 0.72 HTT (0.77) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL31166012 0.72 HTT (0.77) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL9602694 0.72 ALDH1A1 (0.63) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL22840673 0.71 HPGD (0.68) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL6727835 0.71 HSD17B3 (0.53) ALOX15HSD17B10TSHRALDH1A1HPGD
SCHEMBL11074148 0.70 HPGD (0.61) ALOX15HSD17B10TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115353-B2 Method for nucleotide detection ILLUMINA, INC. (US) 2015-08-25 US disclosed