Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1772304 | 0.89 | GPR119 (0.41) | YAP1PRMT5KLK7LMNAHPGD | |
| SCHEMBL1773414 | 0.89 | YAP1 (0.47) | YAP1PRMT5LMNAGRIN2BKDM4E | |
| SCHEMBL1771803 | 0.87 | YAP1 (0.40) | YAP1PRMT5KLK7LMNAGRIN2B | |
| SCHEMBL12019295 | 0.86 | ITGB3 (0.39) | PRMT5LMNAHPGD | |
| SCHEMBL1773479 | 0.86 | YAP1 (0.46) | YAP1PRMT5KLK7LMNAKDM4E | |
| SCHEMBL1773046 | 0.86 | YAP1 (0.44) | YAP1PRMT5KDM4E | |
| SCHEMBL1772065 | 0.85 | HRH3 (0.38) | YAP1PRMT5GRIN2BKDM4E | |
| SCHEMBL1772712 | 0.84 | KLK7 (0.40) | YAP1PRMT5KLK7KDM4E | |
| SCHEMBL1773245 | 0.83 | YAP1 (0.47) | YAP1PRMT5LMNAGRIN2BKDM4E | |
| SCHEMBL1772598 | 0.82 | YAP1 (0.45) | YAP1PRMT5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492266-B1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2015-08-26 | — | — | EP | disclosed |