Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216906 | 0.80 | TSHR (0.44) | TSHRMEN1KMT2ATDP1CES2 | |
| SCHEMBL16361836 | 0.75 | CES2 (0.42) | TSHRMEN1KMT2ATDP1CES2 | |
| SCHEMBL9972945 | 0.75 | TSHR (0.40) | TSHRMEN1KMT2ATDP1CES2 | |
| SCHEMBL14678851 | 0.74 | TSHR (0.43) | TSHRMEN1KMT2ATDP1CES2 | |
| SCHEMBL14678852 | 0.72 | TSHR (0.45) | TSHRMEN1KMT2ATDP1CES2 | |
| SCHEMBL36378 | 0.70 | TSHR (0.41) | TSHRMEN1KMT2ATDP1CES2 | |
| SCHEMBL21905156 | 0.68 | HSD17B10 (0.36) | TSHRTDP1CES2ALDH1A1 | |
| SCHEMBL27563505 | 0.68 | ALDH1A1 (0.43) | TSHRMEN1KMT2ATDP1CES2 | |
| SCHEMBL11597640 | 0.67 | TSHR (0.43) | TSHRMEN1KMT2ATDP1CES2 | |
| Ammonia Solution, Strong SCHEMBL28248603 | 0.67 | ALDH1A1 (0.42) | TSHRMEN1KMT2ATDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2911002-A1 | RESIST COMPOSITION | Mitsubishi Gas Chemical Company, Inc. (JP) | 2015-08-26 | — | — | EP | disclosed |